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Anabolic steroids are synthetic substances related to male sex hormones (androgens). Although it is illegal in the United States to possess or distribute anabolic steroids for nonmedical use, a "black market" for them exists, and many amateur and professional athletes take them to enhance performance. In many cases, the athletes take doses that are extremely high—perhaps 100 times the doses that might be prescribed for medical use. As a result, they put themselves in real danger of short-term and long-term health problems. Blood testing, as has been used in the Olympic Games, can detect, identify, and quantify the presence of anabolic steroids in the blood of athletes, which can lead to the disqualification of an athlete.
Many hormones and their structural and functional analogs are used as medication . The most commonly prescribed hormones are estrogens and progestogens (as methods of hormonal contraception and as HRT ),  thyroxine (as levothyroxine , for hypothyroidism ) and steroids (for autoimmune diseases and several respiratory disorders ). Insulin is used by many diabetics . Local preparations for use in otolaryngology often contain pharmacologic equivalents of adrenaline , while steroid and vitamin D creams are used extensively in dermatological practice.