Effect of anabolic steroids

A common side effect we hear a lot about is in regards to anabolic steroids possible negative effect on the liver. While this can be a problem its important to understand why and what you can do to prevent it. While steroids side effects surrounding the liver are very real, in-short the largest cause for this problem is the use of oral anabolic steroids; in general, injectable steroids will not cause a problem. Further, this does not mean we cannot use oral anabolic steroids but abuse of orals is a higher risk than with injectables. By keeping our oral steroid use to one oral at a time, using orals for shorter durations as well as taking an herbal liver support supplement will greatly ease any negative steroids side effects you may incur with steroid use.

After 1935 the best method of discovering and measuring the protein-building action of androgenic steroids in humans proved to be metabolic balance studies. In 1955, when anabolic steroids with less androgens were developed, the nitrogen-balance method was used again to evaluate and compare the nitrogen-sparing effect of the various preparations. The findings of the numerous balance studies that were performed are as follows: The injectable 17 beta-esters, such as nandrolone phenylpropionate, nandrolone decanoate and methenolone oenanthate exert a strong anabolic action for several weeks, amounting to 2- g nitrogen/day, which corresponds to a daily gain of 12-15 g protein or 60-75 g lean body mass. The orally active 17-alkyl derivatives induce a dose-dependent nitrogen-saving effect of the same order. While the drug is being administered, nitrogen-, calcium- and phosphorus-balance studies in osteoporotic patients show calcium and phosphorus retention in most cases. Anabolic steroids can abolish a negative nitrogen balance brought about by the administration of corticosteroids and anti-androgens. They thus possess anti-catabolic properties. Nitrogen loss after surgical procedures and following accidental traumata can be significantly reduced by pre-operative or post-operative treatment with anabolic agents. Comparison of the metabolic balance method with isotope studies showed a satisfactorily positive correlation. Later calcium metabolism studies in osteoporotic patients were mostly performed with various methods such as in vivo neutron activation analysis and osteodensitometry. They confirm the calcium anabolic effect of certain anabolic steroids.

As a non-aromatizing androgen, dihydrotestosterone is extremely potent. Aromatization refers to the conversion of testosterone or anabolic steroids into estrogen. High estrogenic activity causes bloating, acne, water retention and oily skin. As dihydrotestosterone does not aromatize even at high dosages, users do not face the aforementioned side-effects. Lack of water retention also has a hardening effect on muscle tissue, in bodybuilders. Being a powerful androgen, dihydrotestosterone is also responsible for a shift in the estrogen-testosterone ratio in the body. Due to its predominant androgenic component, the steroid has a stimulating effect on the adreno-pituitary functions, and causes neurological excitation in the ‘sexual orientation areas of the brain’. This in turn, spikes sex drive in males.

Acne is often present. Acne conglobata is a particularly severe form of acne that can develop during steroid abuse or even after the drug has been discontinued. Infections are a common side effect of steroid abuse because of needle sharing and unsanitary techniques used when injecting the drugs into the skin. These are similar risks to IV drug abusers with increased potential to acquire blood-borne infections such as hepatitis and HIV/AIDS . Skin abscesses may occur at injection sites and may spread to other organs of the body. Endocarditis or an infection of the heart valves is not uncommon.

Effect of anabolic steroids

effect of anabolic steroids

Acne is often present. Acne conglobata is a particularly severe form of acne that can develop during steroid abuse or even after the drug has been discontinued. Infections are a common side effect of steroid abuse because of needle sharing and unsanitary techniques used when injecting the drugs into the skin. These are similar risks to IV drug abusers with increased potential to acquire blood-borne infections such as hepatitis and HIV/AIDS . Skin abscesses may occur at injection sites and may spread to other organs of the body. Endocarditis or an infection of the heart valves is not uncommon.

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